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Microbiome in Head and Neck Cancer: Pathogenesis, Diagnosis and Therapeutic Implications

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  • ISBN: 9780443470523
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Microbiome in Head and Neck Cancer: Pathogenesis, Diagnosis and Therapeutic Implications

, Volume 169 in the Advances in Immunology series, presents an authoritative exploration of how microbial communities contribute to the initiation, progression, and treatment of head and neck cancers.

This volume examines the composition and dynamics of the head and neck microbiome, key factors driving dysbiosis, and mechanistic links to oral potentially malignant disorders (OPMDs) and oral squamous cell carcinoma (OSCC).

Chapters highlight emerging microbial biomarkers for early detection, the prognostic value of microbiome profiles, and innovative diagnostic and therapeutic approaches, including microbiome modulation and AI-based data analysis.

Together, these insights provide clinicians, immunologists, oncologists, and cancer researchers with a comprehensive resource on the immunological and microbial interplay underlying head and neck malignancies.

Section I: Introduction to the Microbiome

1. Introduction

2. The Microbiome of the Head and Neck Region

3. Overview of Head and Neck Microbiota

4. Factors Influencing the Head and Neck Microbiome

5. Mechanistic Pathways of Dysbiosis in Cancer Development

Section II: Oral Microbiota and OPMDs

6. Oral Potentially Malignant Disorders (OPMDs): An Overview

7. Oral Microbiome in Various OPMDs

8. Microbial Biomarkers for OPMD Progression

Section III: Oral Microbiota and Oral Cancer

9. Oral Squamous Cell Carcinoma (OSCC): An Overview

10. Role of the Oral Microbiome in Oral Cancer (OSCC)

11. Microbiome as a Prognostic Indicator in Oral Cancer

Section IV: Diagnostic and Therapeutic Applications

12. Microbiome-Based Diagnostic Approaches

13. Modulating the Head and Neck Microbiome for Cancer Prevention

14. Microbiome-Targeted Therapeutics in Head and Neck Cancer

15. Artificial Intelligence in Microbiome Data Analysis: Applications in Head and Neck Cancer

16. Challenges and Future Directions in Head & Neck Microbiome Research

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