Middleton's Allergy 2-Volume Set

332.99 LEI

369.99 LEI

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As both a practical reference for clinicians and researchers and an effective self-assessment tool for board preparation, Middleton's Allergy: Principles and Practice remains the #1 authoritative resource in the field.

This fully revised 10th Edition brings you up to date with recent advancements in basic science and clinical applications regarding allergy practice and disease mechanisms, offering unparalleled guidance on the full spectrum of allergy across the lifespan.

Uses a concise, logically organized, and consistent chapter structure, with each chapter featuring an opening outline and Summary of Important Concepts boxâall designed to make this comprehensive text easily navigable for learning, research, and clinical application
Contains new content on COVID-19, vaccines, the microbiome, and allergic diseases as related to the effects of climate change, as well as thorough updates throughout the text
Addresses recent innovations in the diagnosis, prevention, and management of allergic disorders, including emerging global issues, the advent of precision medicine, and new immunologic therapies
Features 730+ full-color illustrations and offers even more multiple-choice questions online with answers and explanations for effective, efficient self-assessment and study
Shares the experience and knowledge of a highly renowned editorial board led by Drs.
A.

Wesley Burks and Robyn E.

O’Hehir in coordination with Drs.

David H.

Broide, Leonard B.

Bacharier, Gurjit K.

Khurana Hershey, and R.

Stokes Peebles, Jr.

The 10^th Edition expands its international perspective with the addition of two new esteemed editors: Drs.

Stephen Durham of UK and MÃ¼beccel Akdis of Switzerland
An eBook version is included with purchase.
The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.

Additional digital ancillary content may publish up to 6 weeks following the publication date

SECTION A: Basic Sciences Underlying Allergy and Immunology

1. Innate Immunity

2. Adaptive Immunity

3. Immunoglobulin Structure and Function

4. Immune Tolerance

5. Cytokines in Allergic Inflammation

6. Cellular Adhesion in Inflammation

7. Chemokines

8. The Complement System

9. Lipid Mediators of Hypersensitivity and Inflammation

10. Molecular Biology and Genetic Engineering

11. Biology of Lymphocytes

12. Innate Lymphoid Cells

13. Antigen-Presenting Dendritic Cells

14. Biology of Mast Cells and Their Mediators

15. Biology of Basophils

16. Biology of Eosinophils

17. Biology of Neutrophils

18. Biology of Monocytes and Macrophages

19. Airway Epithelial Cells

20. Airway Smooth Muscle in Asthma

21. Pathophysiology of Allergic Inflammation

22. Genetics and Epigenetics in Allergic Diseases

23. Omic and Systems Biology Approaches to Allergic Disease

24. Immunobiology of IgE and IgE Receptors

25. Neuronal Control of Airway Function in Allergy

SECTION B: Aerobiology and Allergens

26. The Structure and Function of Allergens

27. Aerobiology of Outdoor Allergens

28. Indoor Allergens

29. Preparation and Standardization of Allergens and Allergen Extracts

30. Air Pollution: Indoor and Outdoor

SECTION C: The Skin

31. Structure of the Skin and Cutaneous Immunology

32. Atopic Dermatitis

33. Contact Dermatitis

34. Urticaria and Angioedema

35. Hereditary Angioedema and Bradykinin-Mediated Angioedema

36. Immune Complexes in Disease

SECTION D: The Eye

37. Allergic Diseases of the Eye

SECTION E: Respiratory Tract

38. The Nose and Control of Nasal Airflow

39. Allergic and Nonallergic Rhinitis

40. Rhinosinusitis and Nasal Polyps

41. Development, Structure, and Physiology in Normal Lung and in Asthma

42. Respiratory Tract Mucosal Immunology

43. Airway Mucus and the Mucociliary System

44. Epidemiology of Asthma and Allergic Diseases

45. Ontogeny of Immune Development and Its Relationship to Allergic Diseases and Asthma

46. Climate Change: Allergic Diseases and Asthma

47. Mouse Models of Allergic Airways Disease

48. Diagnosis of Asthma in Infants and Children

49. Management of Asthma in Infants and Children

50. Diagnosis of Asthma in Adults

51. Management of Asthma in Adolescents and Adults

52. Emergency Treatment and Approach to the Patient with Acute Asthma

53. Approach to the Patient with Exercise-Induced Bronchoconstriction

54. Asthma and Allergic Diseases during Pregnancy

55. Occupational Allergy and Asthma

56. Pathology of Asthma

57. Allergic Bronchopulmonary Aspergillosis, Hypersensitivity Pneumonitis and Epidemic Thunderstorm Asthma

58. Immunologic Nonasthmatic Diseases of the Lung

59. Approaches to the Patient with Chronic Cough

60. Bronchial and Nasal Challenge Testing

61. Lung Imaging

62. Aerosols and Aerosol Drug Delivery Systems

SECTION F: Gastrointestinal Tract

63. Gastrointestinal Mucosal Immunology

64. Eosinophilic Gastrointestinal Disorders

SECTION G: Systemic Disease

65. Clinical Significance of Immunoglobulin E

66. In Vivo Methods for the Study and Diagnosis of IgE-mediated Allergy

67. Approach to the Patient with Recurrent Infections

68. Primary Immunodeficiency Diseases

69. Treatment of Primary Immunodeficiency Diseases

70. HIV Infection and Allergic Disease

71. Laboratory Tests for Allergic and Immunodeficiency Diseases

72. Eosinophilia and Eosinophil-Related Disorders

73. Mastocytosis

74. Anaphylaxis

75. Insect Allergy

76. Drug Allergy

77. Hypersensitivity to Aspirin and Other Nonsteroidal Antiinflammatory Drugs

78. Reactions to Foods

79. Oral Food Challenge Testing

80. Food Allergy Management, Prevention and Therapy

81. Adverse Reactions to Vaccines

SECTION H: Therapeutics

82. Allergen Immunotherapy for Inhalant Allergens

83. Principles of Pharmacotherapeutics

84. Precision Medicine in Allergic Disorders

85. Optimizing Adherence in Practice

86. Anti-Immunoglobulin E Therapy

87. Cytokine-Specific Therapy in Asthma

88. Histamine and Antihistamines

89. Inhaled Î²2-Agonists

90. Anticholinergic Therapies

91. Glucocorticoids

92. Antileukotriene Therapy in Asthma

93. Unconventional Theories and Unproven Methods in Allergy

94. Complementary and Integrative Health

APPENDIX A: CD Molecules
(E-ONLY) Answers to Self-Assessment Questions

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