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PNH and the GPI-Linked Proteins

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Description

Paroxysmal Nocturnal Hemoglobinuria (PNH) has been recognized for over a century.

This mysterious disease is now understood at the level of the gene and the protein.

The pathophysiology is related to a class of cell surface proteins with distinctive biochemical and physical characteristics.

Recently it has been acknowledged that PNH is not rare, and once sensitive assays--based on the chemistry of the proteins--can be applied to many patients.


Written by international experts in the field, this book includes a number of distinctive characteristics, such as the clinical features of PNH, the mechanism of hemolysis, the biochemistry of glycosylphosphoinositol anchors, and the chemistry and biophysics of GPI-anchored proteins.


This unique and timely volume will have a wide audience, including hematologists and oncologists with a clinical interest in this disease, as well as basic biochemists, immunologists, and cell biologists studying this class of proteins.

Details
  • ISBN: 9780127729404
Sold By: Prior Books Total Items: 86171

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