Most neurodegenerative diseases have animal parallels such as Alzheimerâs in chimpanzees, multiple sclerosis in macaques, Lou Gehrigâs disease in dogs, but nothing like Parkinsonâs has ever been seen in any species but humans.
Synuclein and the Coelacanth: The Molecular and Evolutionary Origins of Parkinson's Disease delves into the causes of Parkinsonâs disease and how the evolution of the human brain has left us uniquely vulnerable.
Genetic risk factors, environmental toxins, and neuroanatomy are woven together in a multidisciplinary discussion that ranges from subatomic physics to socioeconomics.
Connections between neurodegenerative disease, neural pathways, and innate immunity are explored.
Finally, the author discusses new therapeutic agents are being developed that hope to go beyond just treating the symptoms of Parkinsonâs and actually halt the disease.
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